Interstitial Lung Disease in Sjogrens Syndrome

Title: Interstitial Lung Disease in Sjogrens Syndrome

Volume: 6 Issue: 2

Author(s): Mandana Nikpour, Susanna M. Proudman, Nicole S. Goh and Haralampos M. Moutsopoulos

Affiliation:

Keywords: Sjogren's syndrome, interstitial lung disease, lymphoproliferative

Abstract: Sjogrens syndrome (SS), whether primary, or secondary to other autoimmune rheumatic diseases, is classically associated with the sicca complex of keratoconjunctivits and xerostomia. However, extraglandular manifestations are also relatively common, affecting up to 25% of patients. In this article, we discuss respiratory system involvement in SS, with a focus on interstitial lung disease (ILD). We review the histopathologic variants, clinical features, diagnosis and treatment of SS-ILD. Novel and emerging diagnostic and prognostic biomarkers for SS-ILD are also discussed. We offer an approach to the management of SS-ILD including possible goals of therapy. We conclude by highlighting areas for future research.

Cite this article as:

Nikpour Mandana, M. Proudman Susanna, S. Goh Nicole and M. Moutsopoulos Haralampos, Interstitial Lung Disease in Sjogrens Syndrome, Current Rheumatology Reviews 2010; 6 (2) . https://dx.doi.org/10.2174/157339710791330687

DOI https://dx.doi.org/10.2174/157339710791330687	Print ISSN 1573-3971
Publisher Name Bentham Science Publisher	Online ISSN 1875-6360