Synthetic Approaches to the 2008 New Drugs

Kevin      K.-C. Liu; Subas      M. Sakya; Christopher      J. O'Donnell; Jin      Li

doi:10.2174/138955709791012201

Abstract

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 18 NCEs marketed in 2008.

Keywords: Synthesis, New Drug, New Chemical Entities, Medicine, Therapeutic Agents

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Mini-Reviews in Medicinal Chemistry

Title: Synthetic Approaches to the 2008 New Drugs

Volume: 9 Issue: 14

Author(s): Kevin K.-C. Liu, Subas M. Sakya, Christopher J. O'Donnell and Jin Li

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Keywords: Synthesis, New Drug, New Chemical Entities, Medicine, Therapeutic Agents

Abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. These new chemical entities (NCEs) provide insights into molecular recognition and also serve as leads for designing future new drugs. This review covers the syntheses of 18 NCEs marketed in 2008.

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K.-C. Liu Kevin, M. Sakya Subas, J. O'Donnell Christopher and Li Jin, Synthetic Approaches to the 2008 New Drugs, Mini-Reviews in Medicinal Chemistry 2009; 9 (14) . https://dx.doi.org/10.2174/138955709791012201