The Synthesis, Reactivity and NMR Investigation on 15N-Thiophosphoramidates

Title: The Synthesis, Reactivity and NMR Investigation on 15N-Thiophosphoramidates

Volume: 6 Issue: 8

Author(s): Tomasz Ruman, Karolina Dlugopolska, Agata Jurkiewicz, Dagmara Kramarz, Tomasz Fraczyk, Andrzej Les and Wojciech Rode

Affiliation:

Keywords: NMR, thiophosphate, tiophosphoramidate, thiophosphorylation

Abstract: Novel 15N-isotope enriched potassium and diammonium thiophosphoramidates were synthesized and their spectroscopic properties, along with reactivity towards several compounds, including histidine, thymidine, glucose and 2- deoxyribose are presented. The application of quantum mechanical DFT calculations for estimation of 31P NMR chemical shifts for several thiophosphoramidate ions and its derivatives are also discussed.

Cite this article as:

Ruman Tomasz, Dlugopolska Karolina, Jurkiewicz Agata, Kramarz Dagmara, Fraczyk Tomasz, Les Andrzej and Rode Wojciech, The Synthesis, Reactivity and NMR Investigation on 15N-Thiophosphoramidates, Letters in Organic Chemistry 2009; 6 (8) . https://dx.doi.org/10.2174/157017809790442943