Abstract
This short review describes the recently reported semi- and total syntheses of naturally occurring triterpenoid saponins. Accent is placed on natural monodesmosidic and bidesmosidic saponins of the oleanane- and lupane-type that possess potent pharmacological properties including cytotoxic and antitumor activities.
Keywords: Natural products, Saponins, Triterpenes, Chemical synthesis, Cytotoxic, Anticancer
Mini-Reviews in Organic Chemistry
Title: Recent Progress in the Synthesis of Naturally Occurring Triterpenoid Saponins
Volume: 6 Issue: 4
Author(s): Charles Gauthier, Jean Legault and Andre Pichette
Affiliation:
Keywords: Natural products, Saponins, Triterpenes, Chemical synthesis, Cytotoxic, Anticancer
Abstract: This short review describes the recently reported semi- and total syntheses of naturally occurring triterpenoid saponins. Accent is placed on natural monodesmosidic and bidesmosidic saponins of the oleanane- and lupane-type that possess potent pharmacological properties including cytotoxic and antitumor activities.
Export Options
About this article
Cite this article as:
Gauthier Charles, Legault Jean and Pichette Andre, Recent Progress in the Synthesis of Naturally Occurring Triterpenoid Saponins, Mini-Reviews in Organic Chemistry 2009; 6 (4) . https://dx.doi.org/10.2174/157019309789371541
DOI https://dx.doi.org/10.2174/157019309789371541 |
Print ISSN 1570-193X |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6298 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Use of Cytokines and Chemokines in the Cancer Immunotherapy
Recent Patents on Anti-Cancer Drug Discovery Transposons for Gene Therapy!
Current Gene Therapy Pathophysiology of Metastatic Bone Disease and the Role of the Second Generation of Bisphosphonates: From Basic Science to Medicine
Current Pharmaceutical Design Design, Synthesis and Anticancer Activity Against the MCF-7 Cell Line of Benzo-Fused 1,4-Dihetero Seven- and Six-Membered Tethered Pyrimidines and Purines
Current Medicinal Chemistry Cancer Regulator MicroRNA: Potential Relevance in Diagnosis, Prognosis and Treatment of Cancer
Current Medicinal Chemistry Down-Regulation of DDR1 Induces Apoptosis and Inhibits EMT through Phosphorylation of Pyk2/MKK7 in DU-145 and Lncap-FGC Prostate Cancer Cell Lines
Anti-Cancer Agents in Medicinal Chemistry Fluorine-18 Labeled Amino Acids for Oncologic Imaging with Positron Emission Tomography
Current Topics in Medicinal Chemistry Therapeutic Targets in Triple Negative Breast Cancer - Where are we now?
Recent Patents on Anti-Cancer Drug Discovery The Epidermal Growth Factor Receptor as a Therapeutic Target in Glioblastoma Multiforme and other Malignant Neoplasms
Anti-Cancer Agents in Medicinal Chemistry HIF-1α and Calcium Signaling as Targets for Treatment of Prostate Cancer by Cardiac Glycosides
Current Cancer Drug Targets Quantization of Angiogenesis and Image Analysis
Current Angiogenesis (Discontinued) Brachial Plexopathy as a Complication of Radiotherapy: A Systematic Review
Current Cancer Therapy Reviews Editorial (Hot Topic: Synthetic, Natural and Related Compounds: New Approach to Chronic Diseases Studies)
Current Topics in Medicinal Chemistry Inhibitors of Cathepsin B
Current Medicinal Chemistry Amrubicin: A Synthetic Anthracyclin Analogue in the Treatment of Extensive Stage Small Cell Lung Cancer
Recent Patents on Anti-Cancer Drug Discovery Editorial [Hot Topic: Anti-Lipogenesis as a Novel Strategy for Cancer Therapy (Guest Editors: Jianghua Liu and Deliang Cao)]
Recent Patents on Anti-Cancer Drug Discovery Advances in Peptide Pharmaceuticals
Current Pharmaceutical Biotechnology Current Strategies in the Modification of PLGA-based Gene Delivery System
Current Medicinal Chemistry The Role of microRNAs in the Diagnosis and Treatment of Malignant Pleural Mesothelioma - A Short Review
MicroRNA Nanomedicine to Overcome Cancer Multidrug Resistance
Current Drug Metabolism