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Recent Patents on Cardiovascular Drug Discovery

Editor-in-Chief

ISSN (Print): 2212-3962
ISSN (Online): 1574-8901

Microbubbles as Drug Delivery Systems in Cerebrovascular Diseases

Author(s): Mariacarmela Spinelli, Christian Demitri, Alessandro Sannino, Luca Peruzzotti-Jametti, Marco Bacigaluppi, Giancarlo Comi and Francesco Corea

Volume 4, Issue 3, 2009

Page: [222 - 233] Pages: 12

DOI: 10.2174/157489009789152221

Price: $65

Abstract

The field of neurovascular ultrasound is growing rapidly with new applications. While ultrasound contrast agents were initially used to overcome poor transcranial bone windows for identification of cerebral arteries, newgeneration microbubbles in combination with innovative contrast-specific ultrasound techniques now enable potential therapeutic procedures. This article will provide a review of recent and emerging developments along with patents in ultrasound technology and contrast-specific therapeutic techniques for cerebrovascular patients.

Keywords: Ultrasonography, contrast agent, microbubbles, molecular imaging, site-targeted therapy, drug delivery, &, gene therapy


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