8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine: Novel Aminobenzopentathiepine having In Vivo Anticonvulsant and Anxiolytic Activities

Title: 8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine: Novel Aminobenzopentathiepine having In Vivo Anticonvulsant and Anxiolytic Activities

Volume: 6 Issue: 6

Author(s): Tatyana M. Khomenko, Tatyana G. Tolstikova, Alexey V. Bolkunov, Margarita P. Dolgikh, Alla V. Pavlova, Dina V. Korchagina, Konstantin P. Volcho and Nariman F. Salakhutdinov

Affiliation:

Keywords: Substituted benzopentathiepins, Anticonvulsive activity, Anxiolytic activity

Abstract: High anticonvulsive and anxiolytic activities of 8-trifluoromethyl-6-amino-benzopentathiepin 5, which can be synthesized by new simple and effective method, have been found. The transformation of the amino group in compound 5 to the amide group drastically changed the biological activity of the compounds.

Cite this article as:

Khomenko M. Tatyana, Tolstikova G. Tatyana, Bolkunov V. Alexey, Dolgikh P. Margarita, Pavlova V. Alla, Korchagina V. Dina, Volcho P. Konstantin and Salakhutdinov F. Nariman, 8-(Trifluoromethyl)-1,2,3,4,5-benzopentathiepin-6-amine: Novel Aminobenzopentathiepine having In Vivo Anticonvulsant and Anxiolytic Activities, Letters in Drug Design & Discovery 2009; 6 (6) . https://dx.doi.org/10.2174/157018009789057544

DOI https://dx.doi.org/10.2174/157018009789057544	Print ISSN 1570-1808
Publisher Name Bentham Science Publisher	Online ISSN 1875-628X