The Use of Intravenous Aminobisphosphonates for the Treatment of Pagets Disease of Bone

Title: The Use of Intravenous Aminobisphosphonates for the Treatment of Pagets Disease of Bone

Volume: 9 Issue: 9

Author(s): Luigi Gennari, Daniela Merlotti, Giuseppe Mossetti, Domenico Rendina, Vincenzo De Paola, Giuseppe Martini and Ranuccio Nuti

Affiliation:

Keywords: Paget's disease of bone, bone turnover, bisphosphonates, zoledronic acid, pamidronate, neridronate

Abstract: Pagets disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain. Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this disorder.

Cite this article as:

Gennari Luigi, Merlotti Daniela, Mossetti Giuseppe, Rendina Domenico, De Paola Vincenzo, Martini Giuseppe and Nuti Ranuccio, The Use of Intravenous Aminobisphosphonates for the Treatment of Pagets Disease of Bone, Mini-Reviews in Medicinal Chemistry 2009; 9 (9) . https://dx.doi.org/10.2174/138955709788922683