A Practical Procedure for Efficient Synthesis of α-Amino Acids

Title: A Practical Procedure for Efficient Synthesis of α-Amino Acids

Volume: 6 Issue: 2

Author(s): Shouxin Liu, Debin Ji, Yihua Yang, Xiaoli Zhen, Xia Tian and Jianrong Han

Affiliation:

Keywords: α-Amino acid, malonate, α-hydroxyimino ester

Abstract: An effective method to prepare racemic α-amino acids was developed. The key reactions involve nitrosation of malonate under basic conditions and reduction of α-hydroxyimino ester derivatives with zinc powder in the presence of acetic anhydride.

Cite this article as:

Liu Shouxin, Ji Debin, Yang Yihua, Zhen Xiaoli, Tian Xia and Han Jianrong, A Practical Procedure for Efficient Synthesis of α-Amino Acids, Letters in Organic Chemistry 2009; 6 (2) . https://dx.doi.org/10.2174/157017809787582744