Abstract
Commercial priorities have been identified as negative factors in drug development. We trace the problem to inattention to sound clinical pharmacology practices. When properly applied, clinical pharmacology and associated drug development sciences can, hand in hand, facilitate success in commercial drug development.
Keywords: Clinical Pharmacology, Alzheimer Disease, Drug Development, acetylcholinesterase (AChE) inhibition, cytoplasmic AChE
Current Alzheimer Research
Title: Resurrecting Clinical Pharmacology As a Context for Alzheimer Disease Drug Development
Volume: 6 Issue: 1
Author(s): Robert E. Becker, Latha K. Unni and Nigel H. Greig
Affiliation:
Keywords: Clinical Pharmacology, Alzheimer Disease, Drug Development, acetylcholinesterase (AChE) inhibition, cytoplasmic AChE
Abstract: Commercial priorities have been identified as negative factors in drug development. We trace the problem to inattention to sound clinical pharmacology practices. When properly applied, clinical pharmacology and associated drug development sciences can, hand in hand, facilitate success in commercial drug development.
Export Options
About this article
Cite this article as:
Becker E. Robert, Unni K. Latha and Greig H. Nigel, Resurrecting Clinical Pharmacology As a Context for Alzheimer Disease Drug Development, Current Alzheimer Research 2009; 6 (1) . https://dx.doi.org/10.2174/156720509787313916
DOI https://dx.doi.org/10.2174/156720509787313916 |
Print ISSN 1567-2050 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5828 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Correlation between Changes of FDG-PET Findings and those of Mini- Mental Status Examination Scores in Patients with Moderate Alzheimer’s Disease: Usefulness of Stereotactic Extraction Estimation
Current Molecular Imaging (Discontinued) Pathophysiology of Diabetic Secondary Complication and their Management
Current Diabetes Reviews CSF Ubiquitin As a Specific Biomarker in Alzheimer's Disease
Current Alzheimer Research Apoptosis and Acute Brain Ischemia in Ischemic Stroke
Current Vascular Pharmacology Accuracy of Telephone-Based Cognitive Screening Tests: Systematic Review and Meta-Analysis
Current Alzheimer Research Inflammatory Biomarkers, Depressive Symptoms and Falls Among the elderly in Panama
Current Aging Science Pathophysiology of Atherosclerosis: The Role of Inflammation
Current Pharmaceutical Design Global Cerebral Ischemia: Synaptic and Cognitive Dysfunction
Current Drug Targets Comparison of Changes in Cognitive Functions of Post-stroke Patients with the Computer-based Cognitive Intervention (PABLO System) and Conventional Cognitive Intervention (Paper-pencil Method)
Current Psychiatry Research and Reviews Influence of Oxidative Stress on Catalytic and Non-glycolytic Functions of Glyceraldehyde-3-phosphate Dehydrogenase
Current Medicinal Chemistry Early Functional and Structural Microvascular Changes in Hypertension Related to Aging
Current Hypertension Reviews Early β-Amyloid-induced Synaptic Dysfunction Is Counteracted by Estrogen in Organotypic Hippocampal Cultures
Current Alzheimer Research Vitamin D: A Pleiotropic Hormone with Possible Psychotropic Activities
Current Medicinal Chemistry Risk Factors for Cardiovascular Disease in Psoriasis: Relation to Inflammation Assessed by the Severity and Duration of Illness
Inflammation & Allergy - Drug Targets (Discontinued) Subject Index to Volume 11
Protein & Peptide Letters Lipid Raft Alterations in Aged-Associated Neuropathologies
Current Alzheimer Research Neural Stem Cells Transplanted in a Mouse Model of Parkinson’s Disease Differentiate to Neuronal Phenotypes and Reduce Rotational Deficit
CNS & Neurological Disorders - Drug Targets Role of Vitamins in Human Health and Nutrition: Sources and Morbidity
Current Nutrition & Food Science The Epidemiology of Adiposity and Dementia
Current Alzheimer Research Targeting Monoamine Oxidases with Multipotent Ligands: An Emerging Strategy in the Search of New Drugs Against Neurodegenerative Diseases
Current Medicinal Chemistry