Chalcones and their Potential Role in Inflammation

C.      Kontogiorgis; M.      Mantzanidou; D.      Hadjipavlou-Litina

doi:10.2174/138955708786141034

Abstract

Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches.

Keywords: Natural/synthetic chalcones, inflammation, anti-inflammatories, antioxidants

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Mini-Reviews in Medicinal Chemistry

Title: Chalcones and their Potential Role in Inflammation

Volume: 8 Issue: 12

Author(s): C. Kontogiorgis, M. Mantzanidou and D. Hadjipavlou-Litina

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Keywords: Natural/synthetic chalcones, inflammation, anti-inflammatories, antioxidants

Abstract: Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches.

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Kontogiorgis C., Mantzanidou M. and Hadjipavlou-Litina D., Chalcones and their Potential Role in Inflammation, Mini-Reviews in Medicinal Chemistry 2008; 8 (12) . https://dx.doi.org/10.2174/138955708786141034