Abstract
A microwave-enhanced, rapid, three-component one-pot condensation method has been developed for the synthesis of 1,3-thiazolidin-4-ones using toluene in open vessels at atmospheric pressure. Applying this methodology, eleven 1,3-oxathiolan-5-ones were also synthesized in good yields.
Keywords: Mercapto Acetic Acid, Thiazolidinones, Microwave irradiation, Arenealdehydes, oxathiolones
Letters in Organic Chemistry
Title: Microwave-Assisted Synthesis of 1,3-Thiazolidin-4-ones and 2-Aryl-1,3-oxathiolan-5-ones
Volume: 5 Issue: 5
Author(s): Wilson Cunico, Walcimar T. Vellasco Junior, Marcele Moreth and Claudia R.B. Gomes
Affiliation:
Keywords: Mercapto Acetic Acid, Thiazolidinones, Microwave irradiation, Arenealdehydes, oxathiolones
Abstract: A microwave-enhanced, rapid, three-component one-pot condensation method has been developed for the synthesis of 1,3-thiazolidin-4-ones using toluene in open vessels at atmospheric pressure. Applying this methodology, eleven 1,3-oxathiolan-5-ones were also synthesized in good yields.
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Cite this article as:
Cunico Wilson, Vellasco Junior T. Walcimar, Moreth Marcele and Gomes R.B. Claudia, Microwave-Assisted Synthesis of 1,3-Thiazolidin-4-ones and 2-Aryl-1,3-oxathiolan-5-ones, Letters in Organic Chemistry 2008; 5 (5) . https://dx.doi.org/10.2174/157017808784872089
DOI https://dx.doi.org/10.2174/157017808784872089 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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