Abstract
Discovery of novel antimicrobial agents effective against infections caused by drug-resistant pathogens is an important objective in drug research field. In order to find new structural classes of antibiotics, a series of novel thioetherlinked carbapenem-oxazolidinone hybrids were synthesized. The structures of the hybrids and intermediates were confirmed by 1H NMR, IR, MS and elemental analysis.
Keywords: Carbapenem, oxazolidinone, antimicrobial agent, hybrid, drug-resistant, synthesis
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