Synthesis of 1-Aminocyclopropyl-Pentanoic and -Heptanoic Acid Derivatives

Martina      Gensini; Laura      Quartara; Maria      Altamura

doi:10.2174/157017808784872034

Author(s): Martina Gensini, Laura Quartara and Maria Altamura

Volume 5, Issue 5, 2008

Page: [328 - 331] Pages: 4

DOI: 10.2174/157017808784872034

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Abstract

Herein we report the synthesis of new (1-amino-cyclopropyl)-pentanoic and -heptanoic acid derivatives by titanium- mediated reductive cyclopropanation of the correspondent amides.

Keywords: Amides, cyclopropanation, titanium, Grignard reagent, amines

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Letters in Organic Chemistry

Title: Synthesis of 1-Aminocyclopropyl-Pentanoic and -Heptanoic Acid Derivatives

Volume: 5 Issue: 5

Author(s): Martina Gensini, Laura Quartara and Maria Altamura

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Keywords: Amides, cyclopropanation, titanium, Grignard reagent, amines

Abstract: Herein we report the synthesis of new (1-amino-cyclopropyl)-pentanoic and -heptanoic acid derivatives by titanium- mediated reductive cyclopropanation of the correspondent amides.

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Gensini Martina, Quartara Laura and Altamura Maria, Synthesis of 1-Aminocyclopropyl-Pentanoic and -Heptanoic Acid Derivatives, Letters in Organic Chemistry 2008; 5 (5) . https://dx.doi.org/10.2174/157017808784872034