An Integrated Rule-Set for Protein Localization in Plasmodium falciparum

Title: An Integrated Rule-Set for Protein Localization in Plasmodium falciparum

Volume: 3 Issue: 2

Author(s): Aditya Rao, Sri Jyothsna Yeleswarapu, Rajgopal Srinivasan and Gopalakrishnan Bulusu

Affiliation:

Keywords: Plasmodium falciparum, protein localization, integrated rule-set, Targetpf

Abstract: Proteins localize to many intracellular and extracellular organelles in the malarial parasite Plasmodium falciparum. Although organellar localization in the parasite has been studied in detail, there is a need for a comprehensive ruleset that captures the different paths and mechanisms used by proteins for localization. This review is an attempt to build such a rule-set through a combination of rules gleaned from literature reports. A prototype localization prediction tool has also been implemented by incorporating certain sequence/composition rules from the rule-set.

Cite this article as:

Rao Aditya, Yeleswarapu Jyothsna Sri, Srinivasan Rajgopal and Bulusu Gopalakrishnan, An Integrated Rule-Set for Protein Localization in Plasmodium falciparum, Current Bioinformatics 2008; 3 (2) . https://dx.doi.org/10.2174/157489308784340685