Abstract
Parasite resistance to antimalarial drugs is a serious threat to human health, and novel agents that act on essential enzymes for parasite metabolism, such as proteases, are attractive targets for drug development. In this work, the antimalarial activity of hydroxyethylamine derivatives have been evaluated in vitro against Plasmodium falciparum W2 clone chloroquine resistant. These results show that the some compounds have moderated activity against malaria parasite.
Keywords: Hydroxyethylamine, Antimalarial, Protease inhibitors
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