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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

A Novel Four Component One-Pot Access to 4,6-diaryl-2-Pyridinone and 4-aryl-5,6,7,8-tetrahydro-2-quinolinones

Author(s): Chao-Guo Yan, Xi-Mei Cai, Qi-Fang Wang and Jing Sun

Volume 5, Issue 4, 2008

Page: [282 - 285] Pages: 4

DOI: 10.2174/157017808784049425

Price: $65

Abstract

An efficient one-pot procedure was developed for the synthesis of 4,6-diaryl-2-pyridinones and 4-aryl-8- arylidene-5,6,7,8-tetrahydro-2- quinolinones based on cyclocondensation reactions of N-ethoxycarbonylmethylpyridinium chloride or N-carbamoylmethyl pyridinium chloride with aromatic aldehydes and substituted acetophenones or cyclohexanone. The multi-component reaction is performed by microwave irradiation with the reaction substances in the system of NH4OAc/HOAc.

Keywords: Pyridine, pyridone, quinolinone, microwave irradiation, multi-component reaction, cyclocondensation


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