Asymmetric Synthesis of β-Aminosulfones Via the Enantioselective Hydrogenation of the Corresponding β-Ketosulfones

Title: Asymmetric Synthesis of β-Aminosulfones Via the Enantioselective Hydrogenation of the Corresponding β-Ketosulfones

Volume: 5 Issue: 3

Author(s): Ridha Touati and Bechir Ben Hassine

Affiliation:

Keywords: Catalysts, ruthenium, asymmetric hydrogenation, β-hydroxysulfones, Mitsunobu amination, β-aminosulfones

Abstract: A series of β-aminosulfones were synthesized with high enantioselectivities via a new approach, which combines asymmetric hydrogenation of β-ketosulfones and Mitsunobu amination reaction of the corresponding β- hydroxysulfones with a significant high control of the stereochemistry.

Cite this article as:

Touati Ridha and Hassine Ben Bechir, Asymmetric Synthesis of β-Aminosulfones Via the Enantioselective Hydrogenation of the Corresponding β-Ketosulfones, Letters in Organic Chemistry 2008; 5 (3) . https://dx.doi.org/10.2174/157017808783955835