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Protein & Peptide Letters

Editor-in-Chief

ISSN (Print): 0929-8665
ISSN (Online): 1875-5305

Effects of Stereochemistry of Sugars on Protein Stabilities

Author(s): Kiyonari Masumoto, Tadashi Ueda, Makiko Nagata, Yuko Yamada, Yuichiro Yoshida, Yoshio Hashimoto and Taiji Imoto

Volume 9, Issue 5, 2002

Page: [435 - 439] Pages: 5

DOI: 10.2174/0929866023408553

Price: $65

Abstract

We investigated thermal stabilities of four proteins in the presence of four kinds of sugars to analyze the mechanism of stabilization of proteins by additives. These proteins were stabilized by the addition of sugars, and the degree of stabilization correlated to the partial molar isentropic compressibility of the sugar.

Keywords: STEREOCHEMISTRY, molar isentropic, thermophile, polyols, lysozyme, exothermic reactions


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