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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Did Quadruplex DNA Play a Role in the Evolution of the Eukaryotic Linear Chromosome?

Author(s): Haribabu Arthanari and Philip H. Bolton

Volume 3, Issue 1, 2003

Page: [1 - 9] Pages: 9

DOI: 10.2174/1389557033405520

Price: $65

Abstract

The current evidence on prokaryotic linear chromosomes, the eukaryotes that do not use telomerase and quadruplex DNA has been considered. This has lead to the suggestion that quadruplex DNA may have played a role in the evolution of the protection linear chromosomes rather than in overcoming the end replication problem.

Keywords: dna, telomere, quadruplex, tetraplex, evolution, linear chromosome

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