Selective Thyroid Hormone Receptor Modulators

Title: Selective Thyroid Hormone Receptor Modulators

Volume: 3 Issue: 14

Author(s): Hikari A.I. Yoshihara and Thomas S. Scanlan

Affiliation:

Keywords: thyroid hormone receptor modulators, hyperthyroidism, strms

Abstract: Thyroid hormone regulates many important processes in vertebrates. Analysis of the symptoms that accompany hypo- and hyperthyroidism, the most common disorders of the thyroid, suggests that there are certain desirable biological effects brought about by an excess or deficiency of thyroid hormone, and that selective thyroid hormone receptor modulators (STRMs) would be potentially useful therapeutic agents. This review will provide an introduction to thyroid hormone biology, and will discuss the chemistry and pharmacology of the first generation STRMs.

Cite this article as:

Yoshihara A.I. Hikari and Scanlan S. Thomas, Selective Thyroid Hormone Receptor Modulators, Current Topics in Medicinal Chemistry 2003; 3 (14) . https://dx.doi.org/10.2174/1568026033451682