The Chemistry and Biology of Rhazinilam and Analogues

Olivier      Baudoin; Daniel      Guenard; Francoise      Gueritte

doi:10.2174/1570193043403226

Abstract

Rhazinilam (1) is a natural substance with unique tubulin-binding properties. The present review describes the isolation and structure elucidation of (1), the available data regarding its biological properties, its semi- and total syntheses and its structure-activity relationships through the synthesis of analogues.

Keywords: rhazinilam, tubulin, structure-activity relationships, semisynthesis, total synthesis, analogues

« Previous

Rights & Permissions Print Cite

Mini-Reviews in Organic Chemistry

Title: The Chemistry and Biology of Rhazinilam and Analogues

Volume: 1 Issue: 3

Author(s): Olivier Baudoin, Daniel Guenard and Francoise Gueritte

Affiliation:

Keywords: rhazinilam, tubulin, structure-activity relationships, semisynthesis, total synthesis, analogues

Abstract: Rhazinilam (1) is a natural substance with unique tubulin-binding properties. The present review describes the isolation and structure elucidation of (1), the available data regarding its biological properties, its semi- and total syntheses and its structure-activity relationships through the synthesis of analogues.

Export Options

Export File:

RIS (for EndNote, Reference Manager, ProCite)

BibTeX

Text

Content:

Citation Only

Citation and Abstract

About this article

Cite this article as:

Baudoin Olivier, Guenard Daniel and Gueritte Francoise, The Chemistry and Biology of Rhazinilam and Analogues, Mini-Reviews in Organic Chemistry 2004; 1 (3) . https://dx.doi.org/10.2174/1570193043403226