Synthetic Approaches to the 2003 New Drugs

Kevin   K.-   C. Liu; Jin      Li; Subas      Sakya

doi:10.2174/1389557043402900

Abstract

New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing new future drugs. To these ends, this review covers the syntheses of 23 NCEs marketed in 2003.

Keywords: synthesis, new drug, new chemical entities, medicine, therapeutic agents

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Mini-Reviews in Medicinal Chemistry

Title: Synthetic Approaches to the 2003 New Drugs

Volume: 4 Issue: 10

Author(s): Kevin K.- C. Liu, Jin Li and Subas Sakya

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Keywords: synthesis, new drug, new chemical entities, medicine, therapeutic agents

Abstract: New drugs are introduced to the market every year and each individual drug represents a privileged structure for its biological target. In addition, these new chemical entities (NCEs) not only provide insights into molecular recognition, but also serve as drug-like leads for designing new future drugs. To these ends, this review covers the syntheses of 23 NCEs marketed in 2003.

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C. Liu K.- Kevin, Li Jin and Sakya Subas, Synthetic Approaches to the 2003 New Drugs, Mini-Reviews in Medicinal Chemistry 2004; 4 (10) . https://dx.doi.org/10.2174/1389557043402900