Synthesis of Ferrocenylbenzenes via Cp*RuCl-Catalyzed Partially Intramolecular Cyclotrimerization of Ferrocenylalkynes

Title: Synthesis of Ferrocenylbenzenes via Cp*RuCl-Catalyzed Partially Intramolecular Cyclotrimerization of Ferrocenylalkynes

Volume: 2 Issue: 3

Author(s): Yoshihiko Yamamoto, Hisashi Kataoka, Keisuke Kinpara, Hisao Nishiyama and Kenji Itoh

Affiliation:

Keywords: ruthenium catalysis, cyclotrimerization, diyne, ferrocenylalkyne, ferrocenylbenzene

Abstract: In the presence of catalytic amounts of Cp*RuCl(cod), the [2 + 2 + 2] cycloaddition of 1,6-diynes with ethynylferrocene proceeded at ambient temperature to afford ferrocenylbenzenes in 62-72% yields. An unsymmetrical 1,6-diyne bearing a ferrocenyl terminal was allowed to react with monoalkynes to give the corresponding meta-substituted cycloadducts selectively as single regioisomers. On the other hand, Bis(ferrocenyl)ruthenacyclopentatriene was formed from a diyne bearing a ferrocenyl group on both terminals and excess Cp*RuCl(cod).

Cite this article as:

Yamamoto Yoshihiko, Kataoka Hisashi, Kinpara Keisuke, Nishiyama Hisao and Itoh Kenji, Synthesis of Ferrocenylbenzenes via Cp*RuCl-Catalyzed Partially Intramolecular Cyclotrimerization of Ferrocenylalkynes, Letters in Organic Chemistry 2005; 2 (3) . https://dx.doi.org/10.2174/1570178053765258