S-Layer Proteins as Key Components of a Versatile Molecular Construction Kit for Biomedical Nanotechnology

Title: S-Layer Proteins as Key Components of a Versatile Molecular Construction Kit for Biomedical Nanotechnology

Volume: 6 Issue: 8

Author(s): B. Schuster, D. Pum, M. Sara and U. B. Sleytr

Affiliation:

Keywords: Crystalline surface layer proteins, artificial virus, biomimetics, bottom-up strategy, S-layer fusion protein, microspheres-based detoxification system, nanobiotechnology

Abstract: Surface (S)-layer proteins and S-layer fusion proteins incorporating functional sequences, self-assemble into monomolecular lattices on solid supports and on various lipid structures. Based on these S-layer proteins, supramolecular assemblies can be constructed which are envisaged for label-free detection systems, as affinity matrix, as anti-allergic immuno-therapeutics, as membrane protein-based screening devices, and as drug targeting and delivery systems.

Cite this article as:

Schuster B., Pum D., Sara M. and Sleytr B. U., S-Layer Proteins as Key Components of a Versatile Molecular Construction Kit for Biomedical Nanotechnology, Mini-Reviews in Medicinal Chemistry 2006; 6 (8) . https://dx.doi.org/10.2174/138955706777935026