Abstract
The copper-catalysed asymmetric conjugate addition of diphenylzinc to 2-cyclohexenone has been carried out with good results. An enantiometric excess of up to 91% was obtained using 5 mol% CuI and 5 mol% phosphine ligand derived from L-proline.
Keywords: copper-catalyzed, conjugate-addition, diphenylzinc, phosphine, ligand
Letters in Organic Chemistry
Title: Enantioselective Copper-catalysed Conjugate Addition of Diphenylzinc to Cyclohexenone
Volume: 2 Issue: 1
Author(s): Xiao-yu Wu, Xiang-guo Li and Gang Zhao
Affiliation:
Keywords: copper-catalyzed, conjugate-addition, diphenylzinc, phosphine, ligand
Abstract: The copper-catalysed asymmetric conjugate addition of diphenylzinc to 2-cyclohexenone has been carried out with good results. An enantiometric excess of up to 91% was obtained using 5 mol% CuI and 5 mol% phosphine ligand derived from L-proline.
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Cite this article as:
Wu Xiao-yu, Li Xiang-guo and Zhao Gang, Enantioselective Copper-catalysed Conjugate Addition of Diphenylzinc to Cyclohexenone, Letters in Organic Chemistry 2005; 2 (1) . https://dx.doi.org/10.2174/1570178053400054
DOI https://dx.doi.org/10.2174/1570178053400054 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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