Fluorinated Nucleosides as Antiviral and Antitumor Agents

Wei-Dong      Meng; Feng-Ling      Qing

doi:10.2174/156802606777951082

Abstract

The synthesis of nucleosides and analogues with fluoride modifications on the surgar moiety are reviewed, and their biological activities as potential antiviral and anti-tumor agents are also discussed.

Keywords: diethylaminosulfur trifluoride (DAST), purine analogues, Carbocyclic nucleosides, L-pyranosyl nucleosides, cyclopropane, DNA and RNA viruses

« Previous Next »

Rights & Permissions Print Cite

Current Topics in Medicinal Chemistry

Title: Fluorinated Nucleosides as Antiviral and Antitumor Agents

Volume: 6 Issue: 14

Author(s): Wei-Dong Meng and Feng-Ling Qing

Affiliation:

Keywords: diethylaminosulfur trifluoride (DAST), purine analogues, Carbocyclic nucleosides, L-pyranosyl nucleosides, cyclopropane, DNA and RNA viruses

Abstract: The synthesis of nucleosides and analogues with fluoride modifications on the surgar moiety are reviewed, and their biological activities as potential antiviral and anti-tumor agents are also discussed.

Export Options

Export File:

RIS (for EndNote, Reference Manager, ProCite)

BibTeX

Text

Content:

Citation Only

Citation and Abstract

About this article

Cite this article as:

Meng Wei-Dong and Qing Feng-Ling, Fluorinated Nucleosides as Antiviral and Antitumor Agents, Current Topics in Medicinal Chemistry 2006; 6 (14) . https://dx.doi.org/10.2174/156802606777951082