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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Aptamer-Based Strategies for Stem Cell Research

Author(s): Ke-Tai Guo, Richard Schafer, Angela Paul, Gerhard Ziemer, Hans P. Wendel, Ke-Tai Guo, Richard Schafer, Angela Paul, Gerhard Ziemer and Hans P. Wendel

Volume 7, Issue 7, 2007

Page: [701 - 705] Pages: 5

DOI: 10.2174/138955707781024481

Price: $65

Abstract

Aptamers have been introduced to analytical applications, target validation, and drug discovery processes and, recently, applied directly as therapeutic agents. Aptamers can be generated by a method called SELEX (Systematic Evolution of Ligands by Exponential Enrichment). This is quite remarkable for such a young technology, which is only created in the early 1990s. This paper reviews recent new applications of aptamers in stem cell research and tissue engineering.

Keywords: Mesenchymal stem cells, aptamer, FACS analysis


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