Myostatin: Biology and Clinical Relevance

Title: Myostatin: Biology and Clinical Relevance

Volume: 6 Issue: 7

Author(s): Gilles Carnac, Stephanie Ricaud, Barbara Vernus and Anne Bonnieu

Affiliation:

Keywords: Myostatin, Muscle, Adipose tissue, Rhabdomyosarcoma, Myostatin antagonism, Myostatin processing and signaling, therapeutic approaches

Abstract: Myostatin is a negative regulator of muscle mass. Important advances in our understanding of thecomplex biology of this factor have revealed the therapeutic potential of antagonizing the myostatin pathway. Herewe present the rationale for evaluating anti-myostatin therapies in human muscle-wasting disorders.

Cite this article as:

Carnac Gilles, Ricaud Stephanie, Vernus Barbara and Bonnieu Anne, Myostatin: Biology and Clinical Relevance, Mini-Reviews in Medicinal Chemistry 2006; 6 (7) . https://dx.doi.org/10.2174/138955706777698642