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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

A Concise Total Synthesis of 7-Substituted Eudistomin Analogs

Author(s): Ryoichi Ando, Ge Li, Ji Song, Wensheng Liao, Rujian Ma, Shu-Hui Chen and Zuozhong Peng

Volume 3, Issue 6, 2006

Page: [455 - 458] Pages: 4

DOI: 10.2174/157017806777828448

Price: $65

Abstract

We report herein an optimized practical synthesis of three novel 7-substituted eudistomin analogs (1-3). The total syntheses of these complex tetracyclic molecules were completed in 22 steps from the requisite 7-substituted indoles.

Keywords: demethylation, diasteroselectivity, Pictet-Spengler cyclization, total Synthesis, Eudistomin analogs


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