Reduction of N-Methoxy-N-Methylamides to the Corresponding Amines with AlCl3/LiAlH4

Title: Reduction of N-Methoxy-N-Methylamides to the Corresponding Amines with AlCl3/LiAlH4

Volume: 3 Issue: 6

Author(s): Maria Caterina Viscomi, Angelo Liguori, Francesca Perri, Adolfo Le Pera, Maria Luisa Di Gioia and Antonella Leggio

Affiliation:

Keywords: lithium aluminium hydride, aluminum chloride, reduction, Weinreb amides, N-Methoxy-N-methylamines

Abstract: Aromatic and aliphatic Weinreb amides are selectively converted into the corresponding N-methoxy- N-methylamines by treatment with lithium aluminium hydride in the presence of aluminium chloride.

Cite this article as:

Caterina Viscomi Maria, Liguori Angelo, Perri Francesca, Le Pera Adolfo, Luisa Di Gioia Maria and Leggio Antonella, Reduction of N-Methoxy-N-Methylamides to the Corresponding Amines with AlCl3/LiAlH4, Letters in Organic Chemistry 2006; 3 (6) . https://dx.doi.org/10.2174/157017806777828466