Synthesis of Polyhydroquinoline Derivatives Under Solvent-Free Conditions

Wei-Yi      Chen; Jun      Lu; Jian-Rong      Jin

doi:10.2174/157017806776114577

Abstract

A series of 1,4- dihydropyridines derivatives have been obtained by the reaction of chalcones with dimedone in the presence of ammonium formate under solvent-free conditions. Each title compound was formed in good yield. The structure of these compounds has been thoroughly studied by X-ray crystallographic analysis.

Keywords: 1,4-dihydropyridines, chalcone, dimedone, solvent-free, crystal structure

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Letters in Organic Chemistry

Title: Synthesis of Polyhydroquinoline Derivatives Under Solvent-Free Conditions

Volume: 3 Issue: 4

Author(s): Wei-Yi Chen, Jun Lu and Jian-Rong Jin

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Keywords: 1,4-dihydropyridines, chalcone, dimedone, solvent-free, crystal structure

Abstract: A series of 1,4- dihydropyridines derivatives have been obtained by the reaction of chalcones with dimedone in the presence of ammonium formate under solvent-free conditions. Each title compound was formed in good yield. The structure of these compounds has been thoroughly studied by X-ray crystallographic analysis.

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Chen Wei-Yi, Lu Jun and Jin Jian-Rong, Synthesis of Polyhydroquinoline Derivatives Under Solvent-Free Conditions, Letters in Organic Chemistry 2006; 3 (4) . https://dx.doi.org/10.2174/157017806776114577