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Letters in Organic Chemistry

Editor-in-Chief

ISSN (Print): 1570-1786
ISSN (Online): 1875-6255

An Asymmetric Synthesis of the γ-Amino-β-hydroxy Acid Segment of Hapalosin

Author(s): Soumyaditya Mula and Subrata Chattopadhyay

Volume 3, Issue 1, 2006

Page: [54 - 55] Pages: 2

DOI: 10.2174/157017806774964468

Price: $65

Abstract

A facile synthesis of the title compound has been developed starting from a homoallylic alcohol that can be conveniently prepared from (R)-cyclohexylidene glyceraldehyde. The key features of the synthesis were its operational simplicity and the use of inexpensive compounds.

Keywords: γ-amino-β-hydroxy acid, asymmetric synthesis, (R)-cyclohexylidene glyceraldehyde, hapalosin


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