Equilibrium Insertion of Nanoscale Objects into Phospholipid Bilayers

Title: Equilibrium Insertion of Nanoscale Objects into Phospholipid Bilayers

Volume: 7 Issue: 5

Author(s): Sergey Pogodin and Vladimir A. Baulin

Affiliation:

Keywords: phospholipid bilayers, nanoparticles, carbon nanotubes, mean field, membranes, self-assembly, peptides, lipids, equilibrium, theory

Abstract: Certain membrane proteins, peptides, nanoparticles and nanotubes have rigid structure and fixed shape. They are often viewed as spheres and cylinders with certain surface properties. Single Chain Mean Field theory is used to model the equilibrium insertion of nanoscale spheres and rods into the phospholipid bilayer. The equilibrium structures and the resulting free energies of the nano-objects in the bilayer allow to distinguish different orientations in the bilayer and estimate the energy barrier of insertion.

Cite this article as:

Pogodin Sergey and A. Baulin Vladimir, Equilibrium Insertion of Nanoscale Objects into Phospholipid Bilayers, Current Nanoscience 2011; 7 (5) . https://dx.doi.org/10.2174/157341311797483871