Abstract
In this article an overview of the analytical methods in lignan analysis is given. Sampling, sample preparation (including extraction and hydrolytic sample work up), chromatographic separation methods and several detection modes are discussed and validation parameters like limits of detection and quantitation, recoveries, repeatability and linear range are compared. The challenges of lignan analysis are discussed, advantages and limitations of the individual approaches are described and state of the art methods are presented with main emphasis on sample preparation. Sources of error in sample work-up will be pointed out and recommendations for analysis of lignans in plant foods will be given.
Keywords: Chromatography, coulometric electrode array detection, databases foods, lignans, mass spectrometry, sample preparation, plant foods, phytoestorgens, flax seeds, lignan analysis
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