Abstract
Organosillicon reagents have been found as versatile catalysts or promoters for a broad range of organic reactions due to their special properties of multifunction. An important application of organosilicon reagents is in the research field of multicomponent reactions (MCRs), which provides a vast number of practical synthesis for different molecular libraries. We present in this review the recent research progress of MCRs employing organosillicon reagents as catalysts or promoters for the first time.
Keywords: Organosilicon, catalysis, promotion, multicomponent reactions, multicomponent reactions (MCRs), trimethylsilyl chloride (TMSCl), tetrahydro pyrimidinones (THPMs), trimethylsilyl iodide (TMSI), TMSOTf, dimethyl acetylene dicarboxylate (DMAD), cyclic ketones, chemo-selective, diastereoseletivity, Carbon Nucleophiles, hexamethyl disiloxane (HMDS)
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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