Target-directed Discovery and Bioprocess Engineering of New Enzymes for Environmentally Benign Production of High-Value Chiral Chemicals

Title: Target-directed Discovery and Bioprocess Engineering of New Enzymes for Environmentally Benign Production of High-Value Chiral Chemicals

Volume: 15 Issue: 14

Author(s): Ling Ou, Hui-Lei Yu and Jian-He Xu

Affiliation:

Keywords: Target-directed discovery, Biocatalysis, Oxidoreductases, Expoxide hydrolases, Glucosidases, Bioprocess engineering, Reductases, Rhodotorula sp. AS2.2241, Bacillus sp. ECU0013, Adzuki Bean Ketone Reductases, Pseudomonas putida ECU1009, Glycolate Oxidase, Alcaligenes sp. ECU0401, Rhodococcus sp. ECU0066, EPOXIDE HYDROLASES

Abstract: Herein we give a brief account of the efforts our group made in recent years to discover novel enzymes and utilize them by bioprocess engineering techniques for stereoselective synthesis of various enantiomerically pure chiral chemicals with high value in a greener manner. Included are discussions on oxidoreductases, expoxide hydrolases and glucosidases in whole cells or isolated form from microorganisms or plants.

Cite this article as:

Ou Ling, Yu Hui-Lei and Xu Jian-He, Target-directed Discovery and Bioprocess Engineering of New Enzymes for Environmentally Benign Production of High-Value Chiral Chemicals, Current Organic Chemistry 2011; 15 (14) . https://dx.doi.org/10.2174/138527211796150598