Preparation and Enantiomeric Excess Determination of Optically Active BINOL and BINOL Derivatives

Brian   E.   Love

doi:10.2174/157017906776819178

Abstract

Methods of preparing 1,1-bi-2-naphthol (BINOL) in optically active form, are reviewed. Preparation of this compound and its derivatives through both resolution and asymmetric synthesis, are discussed. Methods of determining the enantiomeric excess of samples of optically active BINOL, both through chromatographic and spectroscopic means, are also reviewed.

Keywords: BINOL, asymmetric synthesis, resolution, enantiomeric excess

« Previous Next »

Rights & Permissions Print Cite

Current Organic Synthesis

Title: Preparation and Enantiomeric Excess Determination of Optically Active BINOL and BINOL Derivatives

Volume: 3 Issue: 2

Author(s): Brian E. Love

Affiliation:

Keywords: BINOL, asymmetric synthesis, resolution, enantiomeric excess

Abstract: Methods of preparing 1,1-bi-2-naphthol (BINOL) in optically active form, are reviewed. Preparation of this compound and its derivatives through both resolution and asymmetric synthesis, are discussed. Methods of determining the enantiomeric excess of samples of optically active BINOL, both through chromatographic and spectroscopic means, are also reviewed.

Export Options

Export File:

RIS (for EndNote, Reference Manager, ProCite)

BibTeX

Text

Content:

Citation Only

Citation and Abstract

About this article

Cite this article as:

Love E. Brian, Preparation and Enantiomeric Excess Determination of Optically Active BINOL and BINOL Derivatives, Current Organic Synthesis 2006; 3 (2) . https://dx.doi.org/10.2174/157017906776819178