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Mini-Reviews in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1389-5575
ISSN (Online): 1875-5607

Geminin as A Molecular Target for the Development of New Anticancer Drugs

Author(s): Kenichi Yoshida

Volume 6, Issue 4, 2006

Page: [461 - 462] Pages: 2

DOI: 10.2174/138955706776361411

Price: $65

Abstract

The unique biological properties of Geminin, particularly as an inhibitor of DNA replication initiation, have been recognized, and this has prompted a number of investigations into this molecule to explore its potential therapeutic as well as diagnostic usefulness. This review summarizes the possibility of Geminin serving as a new molecular target in the development of new anticancer drugs.

Keywords: Geminin, Cdt1, DNA replication, Cancer cell, Peptide


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