Abstract
Pyrazoles are of considerable interest due to the broad variety of their biological activities. This overview summarizes structures of pharmacologically interesting pyrazoles, natural products, technically applied pyrazoles as well as pyrazole syntheses published during the last decade. In addition, new insights into the properties such as tautomerisms, conformations, pyrolyses and decomposition reactions of pyrazoles are reviewed.
Keywords: Condensation, Diazo Compounds, 1,3-Dipolar Cycloaddition, Hydrazines, N-Heterocyclic Carbene, Natural Products, Rearrangement, Regiochemistry, hydroxyl function, pyrazole-trifluoroacetic acid clusters, Withasomnine, Withania somnifera (Solanaceae), methoxywithasomnine, Newbouldia laevis, Discopodium penniervium, Suberites vestigium, Elytraria acaulis
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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