Biofabrication of Silver Nanoparticles by Opuntia ficus-indica: In vitro Antibacterial Activity and Study of the Mechanism Involved in the Synthesis

Title: Biofabrication of Silver Nanoparticles by Opuntia ficus-indica: In vitro Antibacterial Activity and Study of the Mechanism Involved in the Synthesis

Volume: 6 Issue: 4

Author(s): Aniket Gade, Swapnil Gaikwad, Vaibhav Tiwari, Alka Yadav, Avinash Ingle and Mahendra Rai

Affiliation:

Keywords: Silver nanoparticles, Opuntia ficus-indica, biogenic, mechanism, bioreduction, antibacterial

Abstract: We report Opuntia ficus-indica mediated synthesis of colloidal silver nanoparticles. Detection and characterization of nanoparticles were carried out by UV-Vis- and Fourier Transform Infra Red Spectroscopy, Scanning Electron Microscopy and X-ray Diffraction analysis respectively. The aim of the present study was synthesis of silver nanoparticles, assessment of their antibacterial activity, and study of possible mechanism involved. The silver nanoparticles in combination with commercially available antibiotics showed a remarkable antibacterial activity. Some of the commercially available antibiotics in combination with silver nanoparticles showed remarkable activity. However, the maximum activity was demonstrated by Ampicillin followed by Streptomycin and Vancomycin. On the basis of the information obtained in this work, two-step mechanism has been proposed as bioreduction and formation of an intermediate complex leading to formation of capped nanoparticles.

Cite this article as:

Gade Aniket, Gaikwad Swapnil, Tiwari Vaibhav, Yadav Alka, Ingle Avinash and Rai Mahendra, Biofabrication of Silver Nanoparticles by Opuntia ficus-indica: In vitro Antibacterial Activity and Study of the Mechanism Involved in the Synthesis, Current Nanoscience 2010; 6 (4) . https://dx.doi.org/10.2174/157341310791659026