Emerging Analytical Separation Techniques with High Throughput Potential for Pharmaceutical Analysis, Part II: Novel Chromatographic Modes

Title: Emerging Analytical Separation Techniques with High Throughput Potential for Pharmaceutical Analysis, Part II: Novel Chromatographic Modes

Volume: 13 Issue: 6

Author(s): Birke Dejaegher, Sigrid Pieters, Yvan Vander Heyden and Bieke Dejaegher

Affiliation:

Keywords: Hydrophilic interaction liquid chromatography (HILIC), supercritical fluid chromatography (SFC), polar organic solvent chromatography (POSC)

Abstract: In this review paper, the high throughput potential of some novel chromatographic modes is surveyed. The modes are Hydrophilic Interaction Liquid Chromatography (HILIC), Supercritical Fluid Chromatography (SFC), and Polar Organic Solvent Chromatography (POSC). Their high throughput potential will be discussed in three domains, i.e. drug discovery, bio-analysis in clinical drug development, and quality control (QC) testing, and is illustrated with some examples.

Cite this article as:

Dejaegher Birke, Pieters Sigrid, Vander Heyden Yvan and Dejaegher Bieke, Emerging Analytical Separation Techniques with High Throughput Potential for Pharmaceutical Analysis, Part II: Novel Chromatographic Modes, Combinatorial Chemistry & High Throughput Screening 2010; 13 (6) . https://dx.doi.org/10.2174/138620710791516030

DOI https://dx.doi.org/10.2174/138620710791516030	Print ISSN 1386-2073
Publisher Name Bentham Science Publisher	Online ISSN 1875-5402