Abstract
The Huisgen 1,3-dipolar cycloaddition of azides and alkynes, one of the most powerful click reactions which result in 1,2,3-triazoles has been widely used in various research areas. Recent years have seen rapid development of click labeling fluorine-18 peptides and some of these novel imaging probes have been evaluated for Positron emission tomography (PET). This mini review is aiming to provide a brief overview on the development of the click labeling fluorine-18 peptides for PET.
Keywords: Positron emission tomography (PET), molecular imaging, Huisgen 1, 3-dipolar cycloaddition, click label, fluorine-18 Peptide
13