Abstract
Multi-component reactions (MCR) performed in water or aqueous medium are surveyed in this review. Several named and new MCR which are mechanistically different have been successfully performed in water or aqueous medium creating diverse molecular skeletons. This protocol couples the benefits of MCR with that of water as solvent for organic transformations, thus facilitating efficient chemical production in environmentally benign way.
Call for Papers in Thematic Issues
Catalytic C-H bond activation as a tool for functionalization of heterocycles
The major topic is the functionalization of heterocycles through catalyzed C-H bond activation. The strategies based on C-H activation not only provide straightforward formation of C-C or C-X bonds but, more importantly, allow for the avoidance of pre-functionalization of one or two of the cross-coupling partners. The beneficial impact of ...read more
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