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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Review Article

Multi-functional Acyl Urea Compounds: A Review on Related Patents, Clinical Trials, and Synthetic Approaches

Author(s): Janvi Rohilla, Rakhi Mishra*, Shruti Varshney, Avijit Mazumder, Rupa Mazumder, Arvind Kumar and Amrinder Kaur

Volume 28, Issue 17, 2024

Published on: 11 June, 2024

Page: [1366 - 1379] Pages: 14

DOI: 10.2174/0113852728307286240517054021

Price: $65

Abstract

Acyl ureas are a well-known class of organic compounds that have drawn a lot of attention recently because of their array of chemical properties and possible multi-use in medicine. The article summarizes the synthetic procedures used to produce various Acyl urea synthons and includes instances of clinical trials, patents, and commercialized medications having Acyl urea and N-acyl urea moiety. This extensive study examines and summarizes research on acyl urea derivatives conducted over the last 20 years from a variety of sources, including PubMed, Google Scholar, and Google Websites. When it comes to the discovery of new chemicals, urea derivatives still require attention compared to other acyl compounds. This review paper aims to provide a comprehensive overview of the various synthetic approaches utilized in the design of an array of acyl ureas to accomplish the same goal. This work summarizes information related to several heteroatom-fused acyl urea compounds, which fortunately will be a very useful resource for chemists and scientists who are interested in acyl urea synthesis and its applications in chemistry.

Graphical Abstract


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