Recent Advances in Chemistry, Mechanism, and Applications of Quantum Dots in
Photodynamic and Photothermal Therapy

Faride      Ranjbari; Farzaneh      Fathi
doi:10.2174/0118715206295598240215112910
Abstract

Semiconductor quantum dots (QD) are a kind of nanoparticle with unique optical properties that have attracted a lot of attention in recent years. In this paper, the characteristics of these nanoparticles and their applications in nanophototherapy have been reviewed. Phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has gained special importance because of its high accuracy and local treatment due to the activation of the drug at the tumor site. PDT is a new way of cancer treatment that is performed by activating light-sensitive compounds named photosensitizers (PS) by light. PSs cause the destruction of diseased tissue through the production of singlet oxygen. PTT is another non-invasive method that induces cell death through the conversion of near-infrared light (NIR) into heat in the tumor situation by the photothermal agent (PA). Through using energy transfer via the FRET (Förster resonance energy transfer) process, QDs provide light absorption wavelength for both methods and cover the optical weaknesses of phototherapy agents.
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DOI https://dx.doi.org/10.2174/0118715206295598240215112910	Print ISSN 1871-5206
Publisher Name Bentham Science Publisher	Online ISSN 1875-5992
Anti-Cancer Agents in Medicinal Chemistry

Recent Advances in Chemistry, Mechanism, and Applications of Quantum Dots in Photodynamic and Photothermal Therapy

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