Abstract
Cardiovascular Disease (CVD) is the leading cause of morbidity and death worldwide and has become a global public health problem. Traditional Chinese medicine (TCM) has been used in China to treat CVD and achieved promising results. Therefore, TCM has aroused significant interest among pharmacologists and medical practitioners. Previous research showed that TCM can regulate the occurrence and development of atherosclerosis (AS), ischemic heart disease, heart failure, myocardial injury, and myocardial fibrosis by inhibiting vascular endothelial injury, inflammation, oxidant stress, ischemia-reperfusion injury, and myocardial remodeling. It is well-known that TCM has the characteristics of multi-component, multi-pathway, and multitarget. Here, we systematically review the bioactive components, pharmacological effects, and clinical application of TCM in preventing and treating CVD.
Current Pharmaceutical Biotechnology
Title:Traditional Chinese Medicine-based Treatment in Cardiovascular Disease: Potential Mechanisms of Action
Volume: 25 Issue: 17
Author(s): Lanlan Li, Yutong Ran, Jiao Wen, Yirui Lu, Shunmei Liu, Hong Li and Min Cheng*
Affiliation:
- School of Basic Medicine Sciences, Weifang Medical University, Weifang, Shandong, 261053, PR China
Abstract: Cardiovascular Disease (CVD) is the leading cause of morbidity and death worldwide and has become a global public health problem. Traditional Chinese medicine (TCM) has been used in China to treat CVD and achieved promising results. Therefore, TCM has aroused significant interest among pharmacologists and medical practitioners. Previous research showed that TCM can regulate the occurrence and development of atherosclerosis (AS), ischemic heart disease, heart failure, myocardial injury, and myocardial fibrosis by inhibiting vascular endothelial injury, inflammation, oxidant stress, ischemia-reperfusion injury, and myocardial remodeling. It is well-known that TCM has the characteristics of multi-component, multi-pathway, and multitarget. Here, we systematically review the bioactive components, pharmacological effects, and clinical application of TCM in preventing and treating CVD.
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Cite this article as:
Li Lanlan, Ran Yutong, Wen Jiao, Lu Yirui, Liu Shunmei, Li Hong and Cheng Min*, Traditional Chinese Medicine-based Treatment in Cardiovascular Disease: Potential Mechanisms of Action, Current Pharmaceutical Biotechnology 2024; 25 (17) . https://dx.doi.org/10.2174/0113892010279151240116103917
DOI https://dx.doi.org/10.2174/0113892010279151240116103917 |
Print ISSN 1389-2010 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4316 |
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