A Review on Role of Inflammation in Coronavirus Disease

Title:A Review on Role of Inflammation in Coronavirus Disease

Volume: 24 Issue: 13

Author(s): Arezoo Lotfi, Pouran Hajian, Laleh Abbasi, Morad Kohandel Gargari, Najmeh Nameh Goshay Fard and Delaram Naderi*

Affiliation:

• Faculty of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran

Abstract: The respiratory illness known as COVID-19 is caused by the novel coronavirus, SARS-CoV-2. While the precise pathogenic mechanism of COVID-19 remains unclear, the occurrence of a cytokine storm subsequent to viral infection plays a pivotal role in the initiation and advancement of the disease. The infection of SARS-CoV-2 induces a state of immune system hyperactivity, leading to an excessive production of inflammatory cytokines. Consequently, the identification of the various signaling pathways implicated in the inflammation induced by COVID-19 will enable researchers to investigate new targets for therapeutic intervention.

Cite this article as:

Lotfi Arezoo, Hajian Pouran, Abbasi Laleh, Gargari Kohandel Morad, Fard Nameh Goshay Najmeh and Naderi Delaram*, A Review on Role of Inflammation in Coronavirus Disease, Endocrine, Metabolic & Immune Disorders - Drug Targets 2024; 24 (13) . https://dx.doi.org/10.2174/0118715303265274231204075802