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Recent Advances in Food, Nutrition & Agriculture

Editor-in-Chief

ISSN (Print): 2772-574X
ISSN (Online): 2772-5758

Review Article

Exploring Scientific Validation of Millets in Contemporary Healthcare: A Traditional Food Supplement

Author(s): Harjeet Singh, Zubair Aalam, Sandip R Baheti, Anurag Chaudhary, Alok Sharma* and S N Murthy

Volume 15, Issue 1, 2024

Published on: 22 January, 2024

Page: [2 - 12] Pages: 11

DOI: 10.2174/012772574X265711231109195603

Price: $65

Abstract

Millets, small-seeded grasses, are gaining interest for their nutrition and health benefits. This abstract provides a comprehensive overview of millets' pharmacological activities, highlighting their rich bioactive compounds. These compounds, including phenolic compounds, flavonoids, and dietary fibers, contribute to antioxidant effects, safeguarding against chronic diseases. Millets also possess anti-inflammatory properties, potentially alleviating conditions, like arthritis and asthma. They show anti-carcinogenic potential, possibly preventing various cancers' development through mechanisms, like apoptosis induction and inhibiting tumor growth. Moreover, millets offer hypolipidemic and hypoglycemic effects, beneficial for managing conditions, such as dyslipidemia and diabetes. Their high dietary fiber and resistant starch content regulate blood lipids and glucose, reducing the cardiovascular risk. Additionally, millets act as antimicrobials, inhibiting pathogens and serving as natural alternatives to synthetic antimicrobials. They exhibit immunomodulatory effects, enhancing immune function and response. Overall, millets' pharmacological properties, including antioxidant, antiinflammatory, anti-carcinogenic, hypolipidemic, hypoglycemic, antimicrobial, and immunomodulatory traits, position them as functional foods with varied health benefits. Further research can integrate millets into preventive and therapeutic approaches for diverse diseases.

Graphical Abstract

[1]
Holes JH, Laing EM, Pearson OE. Sorghum and the millets: Their composition and nutritive value. London: Academic Press 1980; pp. 877-965.
[2]
Bandyopadhyay T, Muthamilarasan M, Prasad M. Millets for next generation climate-smart agriculture. Front Plant Sci 2017; 8: 1266.
[http://dx.doi.org/10.3389/fpls.2017.01266] [PMID: 28769966]
[3]
de Munter JSL, Hu FB, Spiegelman D, Franz M, van Dam RM. Whole grain, bran, and germ intake and risk of type 2 diabetes: A prospective cohort study and systematic review. PLoS Med 2007; 4(8): e261.
[http://dx.doi.org/10.1371/journal.pmed.0040261] [PMID: 17760498]
[4]
Newby PK, Maras J, Bakun P, Muller D, Ferrucci L, Tucker KL. Intake of whole grains, refined grains, and cereal fiber measured with 7-d diet records and associations with risk factors for chronic disease. Am J Clin Nutr 2007; 86(6): 1745-53.
[http://dx.doi.org/10.1093/ajcn/86.5.1745] [PMID: 18065595]
[5]
Pereira MA, Jacobs DR Jr, Pins JJ, et al. Effect of whole grains on insulin sensitivity in overweight hyperinsulinemic adults. Am J Clin Nutr 2002; 75(5): 848-55.
[http://dx.doi.org/10.1093/ajcn/75.5.848] [PMID: 11976158]
[6]
Sahyoun NR, Jacques PF, Zhang XL, Juan W, McKeown NM. Whole-grain intake is inversely associated with the metabolic syndrome and mortality in older adults. Am J Clin Nutr 2006; 83(1): 124-31.
[http://dx.doi.org/10.1093/ajcn/83.1.124] [PMID: 16400060]
[7]
Backes AC, Abbasi F, Lamendola C, McLaughlin TL, Reaven G, Palaniappan LP. Clinical experience with a relatively low carbohydrate, calorie-restricted diet improves insulin sensitivity and associated metabolic abnormalities in overweight, insulin resistant South Asian Indian women. Asia Pac J Clin Nutr 2008; 17(4): 669-71.
[PMID: 19114407]
[8]
Dixit AA, Azar KMJ, Gardner CD, Palaniappan LP. Incorporation of whole, ancient grains into a modern Asian Indian diet to reduce the burden of chronic disease. Nutr Rev 2011; 69(8): 479-88.
[http://dx.doi.org/10.1111/j.1753-4887.2011.00411.x] [PMID: 21790614]
[9]
Bugusu BA, Campanella O, Hamaker BR. Improvement of sorghum-wheat composite dough rheological properties and breadmaking quality through zein addition. Cereal Chem 2001; 78(1): 31-5.
[http://dx.doi.org/10.1094/CCHEM.2001.78.1.31]
[10]
Shahidi F, Naczk M. Phenolics in cereals and legumesFood Phenolics Sources, effects, applications. Technomic Publishing Co 1995; pp. 9-52.
[11]
Huang MT, Ferraro T, Ho CT, Lee CY. Phenolics compounds in food and cancer prevention. ACS Symposium Series 1992; 57: 8-34.
[http://dx.doi.org/10.1021/bk-1992-0507.ch002]
[12]
Klopfenstein CF, Hoseney RC. Nutritional properties of sorghum and the milletsSorghum and Millets: Chemistry and Technology. St Paul, MN: American Association of Cereal Chemists 1995; pp. 125-68.
[13]
Stapf O, Hubbard CE. The Flora of Tropical Africa. Landon: Crown Agents 1934; 9: pp. 954-1070.
[14]
Bor NL. The Grasses of Burma, Ceylon, India and Pakistan. In: International Monograph on Pure and Applied Biology. Pergamon Press 1960; 547: pp. 576-83.
[15]
Sood S, Khulbe RK, Gupta AK, Agrawal PK, Upadhyaya HD, Bhatt JC. Barnyard millet: A potential food and feed crop of future. Plant Breed 2015; 134(2): 135-47.
[http://dx.doi.org/10.1111/pbr.12243]
[16]
Yadav OP, Rai KN, Bidinger FR, Gupta SK, Rajpurohit BS, Bhatnagar SK. Pearl millet (Pennisetum glaucum) restorer lines for breeding dual-purpose hybrids adapted to arid environments. Int J Agric Sci 2012; 82: 922-7.
[17]
Begg JE. The growth and development of a crop of bulrush millet (Pennisetum typohoides S. & H.). Indian J Agric Sci 1965; 65(3): 341-9.
[18]
Clayton WD. Gramineae In: Flora of West Tropical Africa. Crown Agents 1972; 1: pp. 170-465.
[19]
Austin DF. Fox-tail millets (Setaria: Poaceae): Abandoned food in two hemispheres. Econ Bot 2006; 60(2): 143-58.
[http://dx.doi.org/10.1663/0013-0001(2006)60[143:FMSPFI]2.0.CO;2]
[20]
Hilu KW, Johnson JL. Systematics of eleusine gaertn. (Poaceae: Chloridoideae): Chloroplast DNA and total evidence. Ann Mo Bot Gard 1997; 84(4): 841-7.
[http://dx.doi.org/10.2307/2992029]
[21]
Bisht MS, Mukai Y. Genome organization and polyploidy evaluation in the genus Eleusine (Poaceae). Plant Syst Evol 2002; 233(3): 243-58.
[http://dx.doi.org/10.1007/s00606-002-0201-5]
[22]
Bala-Ravi S. Neglected millets that save the poor from starvation. LEISA India 2004; 6(1): 1-8.
[23]
Agricultural Statistics, Government of India. “Pearl Millet,” in Agricultural Statistics at a Glance-2014, Government of India. New Delhi: Oxford University Press 2014; pp. 85-6.
[24]
Yang XS, Wang LL, Zhou XR, et al. Determination of protein, fat, starch, and amino acids in foxtail millet [Setaria italica (L.) Beauv. by Fourier transform near-infrared reflectance spectroscopy. Food Sci Biotechnol 2013; 22(6): 1495-500.
[http://dx.doi.org/10.1007/s10068-013-0243-1]
[25]
Chandrasekara A, Naczk M, Shahidi F. Effect of processing on the antioxidant activity of millet grains. Food Chem 2012; 133(1): 1-9.
[http://dx.doi.org/10.1016/j.foodchem.2011.09.043]
[26]
Clayton WD, Renvoize SA. Genera Graminum: Grasses of the world. Kew Bulletin Additional Series 1986; 13: 389.
[27]
Yabuno T. Japanese barnyard millet (Echinochloa utilis, poaceae) in Japan. Econ Bot 1987; 41(4): 484-93.
[http://dx.doi.org/10.1007/BF02908141]
[28]
Balten Sperger DD. Progress with proso, pearl and other millets. In trends in new crops and new uses Proceedings of the Fifth National Symposium,. Atlanta, Georgia, USA, ASHS Press 10-13 November, 2001-2002, 100-103.
[29]
de Wet JMJ, Brink DE, Rao KEP, Mengesha MH. Diversity in Kodo millet,Paspalum scrobiculatum. Econ Bot 1983; 37(2): 159-63.
[http://dx.doi.org/10.1007/BF02858779]
[30]
Vijayakumari J, Mushtari Begum J, Begum S, Gokavi S. Sensory attributes of ethinic foods from finger millet (Eleusine coracana). Recent Trends in Millet Processing and utilization. >InProceeding of national seminar on processing and utilization of millet for nutrition security held on October 2003; 7-8.
[31]
Dwivedi S, Upadhyaya H, Senthilvel S, Hash C, Fukunaga K, Diao X. Millets. Genetic and Genomic Resources 2011; 35(5): 247-375.
[32]
Santra DK. Proso millet varieties for western Nebraska western Nebraska. 2013. Available from: http://www.ianrpubs.unl.edu/epublic/live/g2219/build/g2 219.pdf
[33]
Correa AD, Jokl L, Carlsson R. Amino acid composition of some Amaranthus sp. grain proteins and of its fractions. Arch Latinoam Nutr 1986; 36(3): 466-76.
[PMID: 3632220]
[34]
Qureshi AA, Lehmann JW, Peterson DM. Amaranth and its oil inhibit cholesterol biosynthesis in 6-week-old female chickens. J Nutr 1996; 126(8): 1972-8.
[PMID: 8759369]
[35]
Bennink MR, Om AS. Inhibition of colon cancer (CC) by soy phytochemicals but not by soy protein. FASEB J 1998; 12(5): 3806.
[36]
Klimczak I, Małecka M, Pachołek B. Antioxidant activity of ethanolic extracts of amaranth seeds. Nahrung 2002; 46(3): 184-6.
[http://dx.doi.org/10.1002/1521-3803(20020501)46:3<184:AIDFOOD184>3.0.CO;2-H] [PMID: 12108218]
[37]
Ohsaki T, Fukuoka S, Bimb HP, Baniya BK, Yasui Y, Ohnishi O. Phylogenetic analysis of the genus Fagopyrum (Polygonaceae), including the Nepali species F. megacarpum, based on nucleotide sequence of the rbcL-accD region in chloroplast DNA. Fagopyrum 2001; 18: 9-14.
[38]
Joshi BK. Buckwheat Genetic Resources: Status and Prospects in Nepal. Agriculture Development Journal 2008; 5: 13-30.
[39]
Nepali B, Bhandari D, Jiban S. Mineral nutrient content of buckwheat (fagopyrum esculentum moench) for nutritional security in Nepal. Malays J Sustain Agricul 2019; 3(1): 01-4.
[40]
Devi PB, Vijayabharathi R, Sathyabama S, Malleshi NG, Priyadarisini VB. Health benefits of finger millet (Eleusine coracana L.) polyphenols and dietary fiber: A review. J Food Sci Technol 2014; 51(6): 1021-40.
[http://dx.doi.org/10.1007/s13197-011-0584-9] [PMID: 24876635]
[41]
Obiana AB. Overview: Importance of millets in Africa. 2003. Available from: http://www.afripro.org.uk/papers/Paper02Obil (Accessed 7 Feb 2020).
[42]
Cisse RS, Hamburg JD, Freeman ME, Davis AJ. Using locally produced millet as a feed ingredient for poultry production in Sub-Saharan Africa. J Appl Poult Res 2017; 26(1): 9-22.
[http://dx.doi.org/10.3382/japr/pfw042]
[43]
Andrews DJ, Kumar KA. Pearl millet for food, feed, and forage. Adv Agron 1992; 48: 89-139.
[http://dx.doi.org/10.1016/S0065-2113(08)60936-0]
[44]
Shivananjappa M. Meats are malady and millets are magical. In: Shivananjappa M, Ed J Nutrit Food Res Technol 2018; 1(1): 14-5.
[http://dx.doi.org/10.30881/jnfrt.00004]
[45]
ICRISAT. Smart food millet recipes. 2016. Available from: http://www.icrisat.org/PDF/Food-Booklet-Millet.pdf (Accessed 16 May 2020).
[46]
Dias-Martins AM, Kênia Letícia P, Sidney P, José Avelino SR, Carlos WPC. Potential use of pearl millet (Pennisetum glaucum (L.) R. Br.) in Brazil: food security, processing, health benefts and nutritional products. Food Res Int 2018; 109: 175-86.
[47]
Kumar A, Tomer V, Kaur A, Kumar V, Gupta K. Millets: A solution to agrarian and nutritional challenges. Agric Food Secur 2018; 7(1): 31.
[http://dx.doi.org/10.1186/s40066-018-0183-3]
[48]
Sehgal A, Kwatra A. Processing and utilization of pearl millet for nutrition security. Proceeding of national seminar on Recent Trend in Millet Processing and Utilization held at CCS HAU, Hissar, India , PP.1-6,. 2003.
[49]
Hadimani NA, Malleshi NG. Studies on milling, physico-chemical properties, nutrient composition and dietary fiber content of millets. J Food Sci Technol 1993; 30: 17-20.
[50]
Singh KP, Mishra HN, Saha S. Changes during accelerated storage in millet–wheat composite flours for bread. Food Bioprocess Technol 2012; 5(5): 2003-11. b
[http://dx.doi.org/10.1007/s11947-011-0769-2]
[51]
Singh P, Raghuvanshi RS. Finger millet for food and nutritional security. Afr J Food Sci 2012; 6(4): 77-84.
[52]
Mbithi-Mwikya S, Ooghe W, Van Camp J, Ngundi D, Huyghebaert A. Amino acid profiles after sprouting, autoclaving, and lactic acid fermentation of finger millet (Eleusine coracan) and kidney beans (Phaseolus vulgaris L.). J Agric Food Chem 2000; 48(8): 3081-5.
[http://dx.doi.org/10.1021/jf0002140] [PMID: 10956072]
[53]
Usha Antony, Sripriya G, Chandra TS. Effect of fermentation on the primary nutrients in finger millet (Eleusine coracana). J Agric Food Chem 1996; 44(9): 2616-8.
[http://dx.doi.org/10.1021/jf950787q]
[54]
Ragaee S, Abdelaal E, Noaman M. Antioxidant activity and nutrient composition of selected cereals for food use. Food Chem 2006; 98(1): 32-8.
[http://dx.doi.org/10.1016/j.foodchem.2005.04.039]
[55]
Krishnan R, Dharmaraj U, Sai Manohar R, Malleshi NG. Quality characteristics of biscuits prepared from finger millet seed coat based composite flour. Food Chem 2011; 129(2): 499-506.
[http://dx.doi.org/10.1016/j.foodchem.2011.04.107] [PMID: 30634257]
[56]
Ravindran G. Seed protein of millets: Amino acid composition, proteinase inhibitors and in-vitro protein digestibility. Food Chem 1992; 44(1): 13-7.
[http://dx.doi.org/10.1016/0308-8146(92)90251-V]
[57]
Hegde PS, Chandra TS. ESR spectroscopic study reveals higher free radical quenching potential in kodo millet (Paspalum scrobiculatum) compared to other millets. Food Chem 2005; 92: 177-82.
[http://dx.doi.org/10.1016/j.foodchem.2004.08.002]
[58]
Dykes L, Rooney LW. Sorghum and millet phenols and antioxidants. J Cereal Sci 2006; 44(3): 236-51.
[http://dx.doi.org/10.1016/j.jcs.2006.06.007]
[59]
Alebiowu G, Itiola OA. The effects of starches on mechanical properties of paracetamol tablet formulations. Sorghum and plantain starch a disintegrantActu. Pharm 2003; 53(3): 231-7.
[PMID: 14769246]
[60]
Choi YY, Osada K, Ito Y, Nagasawa T, Choi MR, Nishizawa N. Effects of dietary protein of Korean foxtail millet on plasma adiponectin, HDL-cholesterol, and insulin levels in genetically type 2 diabetic mice. Biosci Biotechnol Biochem 2005; 69(1): 31-7.
[http://dx.doi.org/10.1271/bbb.69.31] [PMID: 15665464]
[61]
Lee SH, Chung IM, Cha YS, Park Y. Millet consumption decreased serum concentration of triglyceride and C-reactive protein but not oxidative status in hyperlipidemic rats. Nutr Res 2010; 30(4): 290-6.
[http://dx.doi.org/10.1016/j.nutres.2010.04.007] [PMID: 20534332]
[62]
Rajasekaran NS, Nithya M, Rose C, Chandra TS. The effect of finger millet feeding on the early responses during the process of wound healing in diabetic rats. Biochim Biophys Acta Mol Basis Dis 2004; 1689(3): 190-201.
[http://dx.doi.org/10.1016/j.bbadis.2004.03.004] [PMID: 15276645]
[63]
Lakshmi Kumari P, Sumathi S. Effect of consumption of finger millet on hyperglycemia in non-insulin dependent diabetes mellitus (NIDDM) subjects. Plant Foods Hum Nutr 2002; 57(3/4): 205-13.
[http://dx.doi.org/10.1023/A:1021805028738] [PMID: 12602929]
[64]
Hegde PS, Rajasekaran NS, Chandra TS. Effects of the antioxidant properties of millet species on oxidative stress and glycemic status in alloxan-induced rats. Nutr Res 2005; 25(12): 1109-20.
[http://dx.doi.org/10.1016/j.nutres.2005.09.020]
[65]
Graf E, Eaton JW. Antioxidant functions of phytic acid. Free Radic Biol Med 1990; 8(1): 61-9.
[http://dx.doi.org/10.1016/0891-5849(90)90146-A] [PMID: 2182395]
[66]
Aburai N, Esumi Y, Koshino H, Nishizawa N, Kimura K. Inhibitory activity of linoleic acid isolated from proso and Japanese millet toward histone deacetylase. Biosci Biotechnol Biochem 2007; 71(8): 2061-4.
[http://dx.doi.org/10.1271/bbb.70068] [PMID: 17690455]
[67]
Mathanghi SK. Nutraceutical properties of great milletSorghum vulgare. IntJ Food Agric Veter Sci 2012; 2(2): 40-5.
[68]
Gómez-Cordovés C, Bartolomé B, Vieira W, Virador VM. Effects of wine phenolics and sorghum tannins on tyrosinase activity and growth of melanoma cells. J Agric Food Chem 2001; 49(3): 1620-4.
[http://dx.doi.org/10.1021/jf001116h] [PMID: 11312905]
[69]
Dayakar RB, Bhaskarachary K, Arlene Christina GD, Sudha Devi G, Tonapi A. Nutritional and Health benefits of millets ICAR Indian Institute of Millets Research (IIMR). Hyderabad: Rajendranagar 2017; p. 112.
[70]
Tsao R. Chemistry and biochemistry of dietary polyphenols. Nutrients 2010; 2(12): 1231-46.
[http://dx.doi.org/10.3390/nu2121231] [PMID: 22254006]
[71]
Issoufou A, Tidjani A, Yong-Hui S, Le G-W. Chemical analysis and antioxidant properties of foxtail millet bran extracts. Songklanakarin J Sci Technol 2011; 33(5): 509515.
[72]
Catassi C, Fasano A. Celiac diseaseGluten-free cereal products and beverages. Burlington, MA: Elsevier 2008; pp. 1-27.
[http://dx.doi.org/10.1016/B978-012373739-7.50003-4]
[73]
Rai S, Kaur A, Chopra CS. Gluten-free products for celiac susceptible people. Front Nutr 2018; 5: 116.
[http://dx.doi.org/10.3389/fnut.2018.00116] [PMID: 30619866]
[74]
Mirmoghtadaie L, Shojaee-Aliabadi S, Hosseini SM, Soltanizadeh N, Mirmoghtadaee P, Banavand P. Gluten-free products in celiac disease: Nutritional and technological challenges and solutions. J Res Med Sci 2018; 23(1): 109.
[http://dx.doi.org/10.4103/jrms.JRMS_666_18] [PMID: 30693044]
[75]
Miaki T, Tanaka S, Kawamura O, Adania K, Ohashi T, Yamauchi K, et al. A comparison of the feeding value of sorghum, pearl millet and maize silages on the basis of milk production. Bulletin of the Faculty of Agriculture. Miyazaki University 1990; 36(2): 361366.
[76]
Singh P, Srivastava S. Nutritional composition of sixteen new varieties of finger millet. J Community Mobilization Sustainable Dev 2006; 1(2): 81-4.
[77]
Nakarani UM, Singh D, Suthar KP, Karmakar N, Faldu P, Patil HE. Nutritional and phytochemical profiling of nutracereal finger millet (Eleusine coracana L.) genotypes. Food Chem 2021; 341(Pt 2): 128271.
[http://dx.doi.org/10.1016/j.foodchem.2020.128271] [PMID: 33166822]
[78]
Coulibaly A, Kouakou B, Chen J. Phytic acid in cereal grains: Structure, healthy or harmful ways to reduce phytic acid in cereal grains and their effects on nutritional quality Am J Plant Nutrit fertiliz technol 2011; 1(1): 1-22.
[79]
Izadi Z, Nasirpour A, Izadi M, Izadi T. Reducing blood cholesterol by a healthy diet. Int Food Res J 2012; 19(1): 29-37.
[80]
Gélinas P, McKinnon CM, Mena MC, Méndez E. Gluten contamination of cereal foods in Canada. Int J Food Sci Technol 2008; 43(7): 1245-52.
[http://dx.doi.org/10.1111/j.1365-2621.2007.01599.x]
[81]
Park KO, Ito Y, Nagasawa T, Choi MR, Nishizawa N. Effects of dietary Korean proso-millet protein on plasma adiponectin, HDL cholesterol, insulin levels, and gene expression in obese type 2 diabetic mice. Biosci Biotechnol Biochem 2008; 72(11): 2918-25.
[http://dx.doi.org/10.1271/bbb.80395] [PMID: 18997420]
[82]
Ito K, Ozasa H, Noda Y, Arii S, Horikawa S. Effects of free radical scavenger on acute liver injury induced by d-galactosamine and lipopolysaccharide in rats. Hepatol Res 2008; 38(2): 194-201.
[PMID: 17727650]
[83]
Amadoubr I, Le M, Le GW. Millets: Nutritional composition, some health benefits and processing: A<br>Review. Emir J Food Agric 2013; 25(7): 501-8.
[http://dx.doi.org/10.9755/ejfa.v25i7.12045]
[84]
Devisetti R, Ravi R, Bhattacharya S. Effect of hydrocolloids on quality of proso millet cookie. Food Bioprocess Technol 2015; 8(11): 2298-308.
[http://dx.doi.org/10.1007/s11947-015-1579-8]
[85]
Thapliyal V, Singh K. Finger millet: Potential millet for food security and power house of nutrients. IntRes Agricul Forest 2015; 2(2)
[86]
Amadou I, Le G-W, Shi Y-H, Gbadamosi OS, Kamara MT, Jin S. Optimized Lactobacillus plantarum Lp6 solid State fermentation and Proteolytic hydrolysis improve some nutritional attributes of soybean protein meal. J Food Biochem 2011; 35(6): 1686-94. b
[http://dx.doi.org/10.1111/j.1745-4514.2010.00493.x]
[87]
Shahidi F, Chandrasekara A. Millet grain phenolics and their role in disease risk reduction and health promotion: A review. J Funct Foods 2013; 5(2): 570-81.
[http://dx.doi.org/10.1016/j.jff.2013.02.004]
[88]
Verma V, Patel S. Nutritional security and value-added products from finger millets (ragi). J Appl Chem 2012; 1(4): 485-9.
[89]
Dayakar Rao B, Ganapathy KN, Patil JV. Sorghum/ Millets: Small Grains, A big Grain. 2013. Available from: www.commodity.com
[90]
Sagar Bhatt DP, Sharma S, Katnoriya CS. Millet products: Traditional medicinal diet for modern lifestyle health issues. Eur J Mol Clin Med 2022; 9(07)
[91]
Younis SA, Kim KH, Shaheen SM, et al. Advancements of nanotechnologies in crop promotion and soil fertility: Benefits, life cycle assessment, and legislation policies. Renew Sustain Energy Rev 2021; 152: 111686.
[http://dx.doi.org/10.1016/j.rser.2021.111686]
[92]
Chandrasekara A, Shahidi F. Determination of antioxidant activity in free and hydrolyzed fractions of millet grains and characterization of their phenolic profiles by HPLC-DAD-ESI-MSn. J Funct Foods 2011; 3(3): 144-58.
[http://dx.doi.org/10.1016/j.jff.2011.03.007]
[93]
Sarita ES, Singh E. Potential of millets: nutrients composition and health benefits. J Scient Innov Res 2016; 5(2): 46-50.
[http://dx.doi.org/10.31254/jsir.2016.5204]
[94]
Dayakar Rao B, Bhaskarachary K, Arlene Christina GD, Sudha Devi G, Vilas AT, Tonapi A. Nutritional and health benefits of millets ICAR_Indian Institute of Millets Research (IIMR). Hyderabad: Rajendranagar 2017; p. 2.
[95]
Srilekha K, Kamalaja T, Uma Maheswari K, Neela Rani R. Nutritional composition of little millet flour. Int Res J Pure Appl Chem 2019; 20(4): 1-4.
[http://dx.doi.org/10.9734/irjpac/2019/v20i430140]
[96]
Chaudhary Kanchan YN. Evaluation of hypoglycemic properties of kodo millet based food products in healthy subjects. IOSR J Pharm 2013; 3(2): 14-20.
[http://dx.doi.org/10.9790/3013-32201420]
[97]
Das S, Khound R, Santra M, Santra D. Beyond bird feed: Proso millet for human health and environment. Agriculture 2019; 9(3): 64.
[http://dx.doi.org/10.3390/agriculture9030064]
[98]
Mohapatra D, Patel AS, Kar A, Deshpande SS, Tripathi MK. Effect of different processing conditions on proximate composition, anti-oxidants, anti-nutrients and amino acid profile of grain sorghum. Food Chem 2019; 271: 129-35.
[http://dx.doi.org/10.1016/j.foodchem.2018.07.196] [PMID: 30236657]
[99]
Ramadoss DP, Sivalingam N. Vanillin extracted from Proso and Barnyard millets induce apoptotic cell death in HT-29 human colon cancer cell line. Nutr Cancer 2019; 1-16.
[http://dx.doi.org/10.1080/01635581.2019.1672763] [PMID: 31604383]
[100]
Yang R, Shan S, Zhang C, Shi J, Li H, Li Z. Inhibitory effects of bound polyphenol from foxtail millet bran on colitis-associated carcinogenesis by the restoration of gut microbiota in mice model. J Agric Food Chem 2020; 68(11): 3506-17.
[http://dx.doi.org/10.1021/acs.jafc.0c00370] [PMID: 32100999]
[101]
Pang M, He S, Wang L, Cao X, Cao L, Jiang S. Physicochemical properties, antioxidant activities and protective effect against acute ethanol-induced hepatic injury in mice of foxtail millet (Setaria italica) bran oil. Food Funct 2014; 5(8): 1763-70.
[http://dx.doi.org/10.1039/C4FO00106K] [PMID: 24909671]
[102]
Akinola SA, Badejo AA, Osundahunsi OF, Edema MO. Effect of preprocessing techniques on pearl millet flour and changes in technological properties. Int J Food Sci Technol 2017; 52(4): 992-9.
[http://dx.doi.org/10.1111/ijfs.13363]
[103]
Thakur P, Kumar K, Dhaliwal HS. Nutritional facts, bio-active components and processing aspects of pseudocereals: A comprehensive review. Food Biosci 2021; 42: 101170.
[http://dx.doi.org/10.1016/j.fbio.2021.101170]

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