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Current Organic Chemistry

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ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

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Short Communication

Synthesis of Epichlorohydrin-based Click-dendrons with Different Functional Groups

Author(s): Evgeny Ocherednyuk*, Vladimir Burilov, Tatiana Shilyaeva, Svetlana Solovieva and Igor Antipin

Volume 27, Issue 11, 2023

Published on: 27 September, 2023

Page: [979 - 982] Pages: 4

DOI: 10.2174/1385272827666230830105808

Price: $65

Abstract

A methodology for synthesizing 1st generation triazole-containing dendrons based on epichlorohydrin with different functional groups was developed using a Cu-catalyzed azide-alkyne cycloaddition reaction (CuAAC) reaction. The proposed methodology uses simple reagents and can serve as a basis for the synthesis of dendrons and dendrimers of higher generations. High reaction yields as well as the cost of starting reagents, make the preparation of such compounds economically and environmentally favorable.

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