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Current Gene Therapy

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ISSN (Print): 1566-5232
ISSN (Online): 1875-5631

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Letter to the Editor

Development of Oral Bio-banks Past, Present and Future; Challenges and Opportunities

Author(s): Gangadhar Baniekal Hiremath, Kondragunta Omkarbabu, Madhavi Hemant Kokate, Baskar Venkidasamy*, Murugesan Krishnan and Arun Murugaiyan

Volume 24, Issue 1, 2024

Published on: 18 August, 2023

Page: [2 - 3] Pages: 2

DOI: 10.2174/1566523223666230801090355

Price: $65

Abstract

Biobank involves collecting, processing, storing, and organizing biosamples, along with relevant personal and health information such as medical history, family records, genetics data, and lifestyle details, for medical research and clinical care. Oral biobanking is a recently evolved field alongside the rising of precision medicine due to recent research findings in oral oncology and other oral complaints, namely caries and periodontal disease. The common samples in oral biobanks are matured and primary teeth, dental pulp cells, oral biopsies, oral rinses, saliva, and swabs from the buccal region. Moreover, biobank should not conceive of as a static collection of samples and data but as a dynamic resource for developing novel techniques that meet current scientific demands through international networking. However, the major bottlenecks associated with oral biobanks are privacy, processing of samples, normalization of data, extended durability of interest markers of banked samples, and financial sustainability of biobanks. Thus in this correspondence, we argue that an alternative approach is urgently needed to protect the interests of many stakeholders.

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[1]
Galloway J. Putting the teeth into the UK Biobank. Prim Dent Care 2011; (1): 6-12.
[http://dx.doi.org/10.1308/135576111794065720] [PMID: 21214973]
[2]
Sivolella S, Scanu A, Xie Z, Vianello S, Stellini E. Biobanking in dentistry: A review. Jpn Dent Sci Rev 2022; 58: 31-40.
[http://dx.doi.org/10.1016/j.jdsr.2021.12.002] [PMID: 35024075]
[3]
Shungin D, Haworth S, Divaris K, et al. Genome-wide analysis of dental caries and periodontitis combining clinical and self-reported data. Nat Commun 2019; 10(1): 2773.
[http://dx.doi.org/10.1038/s41467-019-10630-1] [PMID: 31235808]
[4]
Czesnikiewicz-Guzik M, Osmenda G, Siedlinski M, et al. Causal association between periodontitis and hypertension: Evidence from mendelian randomization and a randomized controlled trial of non-surgical periodontal therapy. Eur Heart J 2019; 40(42): 3459-70.
[http://dx.doi.org/10.1093/eurheartj/ehz646] [PMID: 31504461]
[5]
Gitter D. The challenges of achieving open source sharing of biobank data. In: Comparative Issues in the Governance of Research Biobanks: Property, Privacy, Intellectual Property, and the Role of Technology. Berlin: Springer 2013; pp. 165-89.
[http://dx.doi.org/10.1007/978-3-642-33116-9_10]

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